Depression

Depression

Depression affects mood, motivation, energy, sleep, and concentration. It can involve sadness, numbness, or loss of interest and is not simply a reaction to stress or a personal weakness. Elderly people may experience depression differently, such as feeling irritable.

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Did you know?

Depression is usually diagnosed and treated based on subjectively reported symptoms, with no regards to what is causing it. Modern brain research shows it involves disrupted activity and communication within and between key brain regions and networks that control mood. The Default Mode Network may become overly focused on self-critical thinking, while the Frontoparietal Control Network shows reduced ability to regulate mood and motivation. Reward-related subnetworks may also be underactive.

So what does this mean?

Depression isn’t one condition with one cause. Network differences explain why people experience depression differently and why a certain medication or style of psychotherapy may help one person but not another.